1	Details of the person discharging managerial responsibilities/person closely associated
a)	Name	Dr. Selwyn Ho
2	Reason for the notification
a)	Position/status	Member of the managing body
b)	Initial notification
3	Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor
a)	Name	Medigene AG
b)	LEI	391200I33JD2DKZGDX06
4	Details of the transaction(s)
a)	Description of the financial instrument, type of instrument	Share
	Identification code	DE000A1X3W00
b)	Nature of the transaction	Purchase
c)	Price(s)	Volume(s)
	2.26 EUR	6,780.00 EUR
d)	Aggregated price	Aggregated volume
	2.26 EUR	6,780.00 EUR
e)	Date of the transaction	14.12.2022 UTC+0
f)	Place of the transaction	London
	MIC	XLON

(end)

Emitter:	Medigene AG Lochhamer Straße 11 82152 Planegg/Martinsried Germany
Contact Person:	Medigene PR/IR
Phone:	+49 89 2000 3333 01
E-Mail:	investor@medigene.com
Website:	www.medigene.de
ISIN(s):	DE000A1X3W00 (Share)
Stock Exchange(s):	Regulated Market in Frankfurt, Free Market in Berlin, Free Market in Dusseldorf, Free Market in Hamburg, Free Market in Hannover, Free Market in Munich, Free Market in Stuttgart, Open Market in Tradegate

Medigene AG: Managers' transactions announcement according to article 19 MAR